We offer equipment and expertise
Our core facilities and units are used for research & development by DTU departments and hospitals, and for commercial diagnostic testing in daily operations.
Development projects & daily operation
High through-put support for PCR & serology
We have liquid handlers as:
- QIAgility
- Biomek 4000
- Biomek i5
- Biomek NXP
- Biomek i7
- TECAN.
We have the expertise to:
- scale up with high sample volume and many data points/assays per samle e.g. research projects, monitoring groups of patients at regular intervals for multiple biomarkers pathogens etc.
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Development projects & daily operation
PCR
For RNA/DNA purification we have:
- QIAcubes
- QIACCube HT
- Biomek i7
- QiaSymphony
- BasePurifier.
For PCR we have:
- Biorad T-100 PCR
- PCR, Rotorgenes
- CFX Opus 96 Real Time PCR
- Biomark Fluidigm + controllers.
We have expertise to:
- develop singleplex and multiplex real-time polymerase chain reaction ((RT)-qPCR) tests that can be applied in diagnostics and research.
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Development projects & daily operation
Biomolecular interaction analysis (BIA)
For assay optimizations we use a Biocore X100 instrument that can mesure binding characteristics of ligands (e.g. antibodies and aptamers) and analytes. Binding characteristics include determination of affinity, binding kinetics and concentration of the ligand or analyte.
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Development projects & daily operation
Serology
Our serology platforms are:
Lateral Flow Assays
The LFA is a commonly used paper-based point-of-care test method for rapid detection of analytes in biological samples such as blood or saliva. The LFA is a simple, cheap and practical detection method that does not require laboratory facilities. The results are displayed within 5-30 minutes.
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Aptamer assays
We have the facilities and expertise to generate oligonucleotide aptamers that can be used instead of antibodies as detection probes for specific and sensitive detection of analytes.
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